Article: Promoter Hypermethylation Profiling Identifies Subtypes of Head and Neck Cancer with Distinct Viral, Environmental, Genetic and Survival Characteristics.

Full Text (publisher's website) ; Article Metadata ; Article Data (extracted)
Choudhury JH; Ghosh SK
PLoS ONE, 2015

10.1371/journal.pone.0129808.t004

Table 4 Correlation between HPV, environmental and genetic characteristics and CIMP-status.

Characteristics	CIMP-H (N = 28)	CIMP-L (N = 30)	CIMP-N (N = 13)	P-values*
Characteristics	CIMP-H (N = 28)	CIMP-L (N = 30)	CIMP-N (N = 13)	CIMP-H vs. CIMP-N	CIMP-L vs. CIMP-N	CIMP-H vs. CIMP-L
Smoking
Yes	25 (89.3)	21 (70)	5 (38.5)
No	3 (10.7)	9 (30)	8 (61.5)	0.008	0.044	0.214
Betel quid chewing
Yes	20 (71.4)	20 (66.7)	7 (53.8)
No	9 (28.6)	10 33.3)	6 (46.2)	0.303	0.249	0.968
Tobacco chewing
Yes	25 (89.3)	22 (73.3)	6 (46.2)
No	3 (10.7)	8 (26.7)	7 (53.8)	0.034	0.207	0.170
GSTM1
Null	22 (78.6)	14 (46.7)	4 (30.8)
Present	6 (21.4)	16 (53.3)	9 (69.2)	0.023	0.731	0.004
GSTT1
Null	10 (35.7)	15 (50)	4 (30.8)
Present	18 (64.3)	15 (50)	9 (69.2)	0.697	0.762	0.281
CYP1A1 (T3801C)
Wild (TT)	8 (28.6)	13 (43.3)	8 (61.5)
Heterozygous (TC)	10 (35.7)	11 (36.7)	4 (30.8)	0.997	0.931	0.910
Variant (CC)	10 (35.7)	6 (20)	1 (7.7)	0.180	0.456	0.256
XRCC1 (Arg399Gln)
Arg/Arg	7 (25)	12 (40)	6 (46.2)
Arg/Gln	14 (50)	11 (36.7)	6 (46.2)	0.108	0.624	0.281
Gln/Gin	7 (25)	7 (23.3)	1 (7.7)	0.056	0.230	0.434
XRCC2 (Arg188His)
Arg/Arg	14 (50)	22 (73.3)	10 (76.9)
Arg/His	14 (50)	8 (26.7)	3 (23.1)	0.402	0.994	0.186

CIMP-H = CIMP-high; CIMP-L = CIMP-low and CIMP-N = CIMP-negative

* P-value was calculated by Chi-square test and further P-value was adjusting for age, gender, HPV, smoking, betel-quid and tobacco chewing status (as appropriate)

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Inferred neuron-electrophysiology data values

Neuron Type	Neuron Description	Ephys Prop	Extracted Value	Standardized Value	Content Source